Pricing · ePROUpdated October 9, 2026

ePRO cost per patient: why a daily diary is not a daily charge

ePRO pricing is usually quoted per patient, per questionnaire or per licence. On Capture, ePRO is included in Core, and the participant fee is per month rather than per entry. That turns the question into cost per completed entry, which falls the more often you ask.

  • ePRO included in Core
  • Cost per entry by frequency
  • No app for participants

Free sandbox · No credit card · 21 CFR Part 11 aligned

ePRO schedule, 12-week study (demo)
AssessmentWk 1Wk 4Wk 8Wk 12
Daily symptom diaryDDDD
Weekly quality-of-life form
Monthly global rating

D = daily diary entries. Cost is per participant-month, not per entry.

More entries per month do not raise the participant fee

The short answer

  • The pricing page includes ePRO and eConsent in Core: $1,000/month (1 live study) plus $50 per participant per month. It shows ePRO as a paid add-on at a typical EDC vendor.
  • The participant fee is per participant-month, not per entry, so asking a participant to complete a diary daily costs the same as asking monthly.
  • Worked example: 60 participants on Core, 12-week diary, $16,000 total ($267 per patient). A daily diary then costs about $3.17 per entry all-in, or $1.79 counting only the participant fee.
  • Because cost does not scale with entries, the cost levers are follow-up length and months live, not the number of questionnaires.
  • Participants complete forms through a secure web link sent by email or SMS; no app store, no install. Reminders go out by email or SMS on the schedule you set.

How ePRO is priced

The usual shapes, and why per-entry thinking misleads

ePRO and eCOA are commonly priced in one of four ways: a licence per study, a fee per participant, a fee per questionnaire or instrument, or per completed assessment. Each rewards a different protocol. A per-assessment price makes a daily diary expensive and a monthly form cheap; a per-participant price does the opposite. When you compare ePRO quotes, convert every one to total cost for your schedule of assessments, then divide by completed entries.

Capture's published model removes the entry from the equation. ePRO sits inside the Core plan next to EDC and eConsent, and the participant fee is monthly. That has a design consequence worth saying out loud: if you have a good scientific reason to collect daily, there is no price penalty for it. The constraint is participant burden and compliance, not invoice size. The patient diary software page covers design for burden, and ePRO software for clinical trials covers the product.

This page is about ePRO in particular. For overall mechanics of the rates, read EDC per-patient pricing explained.

Worked example

60 participants, 12-week ePRO study on Core

Enrolment over 4 months, 3 months of follow-up each, so the study is live for 7 months. List-rate arithmetic, not a quote.

LineQuantityRateAmount
Core monthly fee (1 live study)7 months live$1,000$7,000
Per-participant fee180 participant-months$50$9,000
Study setup by the team1$0$0
ePRO moduleIncluded$0$0
Total$16,000
Per patient (60)$267

The ePRO module itself adds $0 to this bill. Validated instruments that need a licence from their rights holder are a separate matter: that licence cost stays with the study documents.

Cost per completed entry

The same $16,000 at four assessment frequencies

Assumes every scheduled entry is completed. In practice compliance is below 100 percent, so cost per completed entry is a little higher.

Frequency (12 weeks)Entries per participantTotal entries (60)All-in cost per entryParticipant fee only per entry
Daily diary845,040$3.17$1.79
Weekly form12720$22.22$12.50
Monthly questionnaire3180$88.89$50.00
Daily diary + weekly form + monthly rating995,940$2.69$1.52

The total does not change between rows; only the number of entries it is spread across does. Cost per entry is a way to read a budget, not how Capture bills.

Draft a diary in the sandbox

Use the AI Study Builder or an ePRO template, set the schedule and reminders and test the participant link. No credit card.

Build your diary free

What the price includes

What is behind "ePRO included"

Participants open a secure web link sent by email or SMS, in any modern browser; there is nothing to install, so there is no app development line. Forms offer ten question types, including linear scales, sliders and date and time fields. You set reminders per form for due, overdue and missed windows and can escalate to the coordinator when a participant stops responding. The compliance side is covered on ePRO compliance reminders by SMS and email.

Study-level costs that people forget sit nearby. Every validated instrument has its own licence terms, and a questionnaire licence is a budget line between you and the rights holder. In Capture the licence number, holder and expiry can be recorded on a patient questionnaire, but Capture does not verify licences or supply licensed wording. Check the terms for each instrument before you finalise the budget. Free starting points are in the template library.

For small studies see ePRO for small clinical trials; for diary-based designs use EDC with built-in ePRO to see how diary data lands in the same casebook as site data.

ePRO compliance dashboard (demo)

Entries due this week

420

Completed

371

Overdue

49

Site 01138/140

99%

Site 02126/140

90%

Site 03107/140

76%

Demo data. Reminders and coordinator alerts target Site 03.

Comparing ePRO quotes

What to ask when ePRO is priced separately

What is the billing unit?

Per study, participant, instrument or assessment. Convert to your schedule.

Are reminders included?

Ask about SMS and email cost per message.

Is there an app to build?

Web-link ePRO avoids app development and device provisioning.

Where does the data go?

Data in the same system as the EDC avoids reconciliation and a second audit trail.

Who pays for instrument licences?

Usually you. Keep it as its own budget line.

What does an amendment cost?

Adding a question or changing a schedule mid-study.

Context

Putting the ePRO line in the wider budget

ePRO is one part of the data-collection cost. For the whole picture, the EDC software pricing guide covers market tiers, EDC cost for a 100-patient trial gives a line-item worksheet, and how much a clinical trial costs places software in the full budget. Rates above 100 participants are lower, though not published; treat the figures here as ceilings.

FAQ

Questions teams ask before they switch

Something not covered here? Ask us directly.

How much does ePRO cost per patient on Capture?

ePRO is included in Core, which is $1,000 per month plus $50 per participant per month. In a 60-participant, 12-week example that is about $267 per patient at list rates, with no separate ePRO charge.

Do I pay more for a daily diary than a monthly questionnaire?

No. The participant fee is per participant per month, not per entry, so the frequency of assessment does not change the bill.

Is ePRO a paid add-on?

Not on Capture. The pricing page shows ePRO as included in Core and Full Platform and as a paid add-on at a typical EDC vendor.

Do participants need to install an app?

No. They open a secure web link sent by email or SMS in any modern browser.

Are reminders extra?

The pricing page lists no separate reminder charge. Email and SMS reminders can be scheduled per form, with coordinator alerts for missed windows.

Who pays for questionnaire licences?

Licences for validated instruments are agreed between you and the rights holder. Capture can record the licence number and expiry on a patient questionnaire but does not verify licences or supply licensed wording.

Can I test an ePRO study before paying?

Yes. The free sandbox includes every feature with no credit card and no time limit; you pay only once you go live.

Ask as often as the science needs

ePRO is included in Core and billed per participant-month, not per entry. Build free and pay once live.

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