Vendor comparison · Patient technologyUpdated September 29, 2026

Looking at Signant Health alternatives? Compare the whole stack

eCOA, eConsent and randomisation are often bought from one patient technology vendor, while EDC comes from another. Capture puts all four in one self-serve platform. Here is what to compare and where it fits.

  • eCOA, eConsent, RTSM and EDC together
  • Self-serve build
  • Free sandbox

Free sandbox · No credit card · 21 CFR Part 11 aligned

Randomization · stratified blocks · 1:1
Site 01

Baseline severity: moderate

Block 7 of 12

Site 01

Baseline severity: severe

Block 4 of 12

Site 02

Baseline severity: moderate

Block 6 of 12

Subject 01-0048 randomized

Blinded

Randomization no.

R-0166

Treatment arm

●●●●●●

Emergency unblinding

Built in for blinded designs, when participant safety requires it.

The short version

  • Signant Health, formerly CRF Health and Bracket, provides patient-facing and site technology for trials, including eCOA, eConsent and randomisation and trial supply management.
  • Teams compare alternatives when they want EDC in the same system, a self-serve build, or pricing that fits smaller and mid-sized studies.
  • Compare how each module works together: one audit trail or several, one set of roles or several, one participant record or several.
  • Capture includes EDC, ePRO, eConsent and randomisation with kit management in one study, with blinded and unblinded roles.
  • Ask every vendor to show a participant going from consent to randomisation to their first questionnaire.

Why teams compare

Integration is where the cost hides

When consent, randomisation, questionnaires and EDC sit in different systems, someone has to make sure a participant is consented before randomisation, that allocations match between systems, and that questionnaire data lines up with visits. Integrations can automate some of that, but they add build time, testing and reconciliation for every study.

In a unified platform, those checks are built into the workflow. A participant cannot be randomised at a site that has not been activated, allocations are logged in the same audit trail as visit data, and questionnaires follow the same visit schedule. See RTSM software.

Blinding across modules

Blinding is easier to protect when one system controls access. In Capture, blinded roles never receive the treatment arm from the server, including in exports, and an unblinded administrator handles the randomisation and medication lists.

Study coordinator

Subject 01-004

Randomized · R-0012

Treatment assignment blinded

KitK-10418

Arm columnNot sent

Unblinded administrator

Subject 01-004

Randomized · R-0012

Treatment: Active (A)

KitK-10418

Arm columnA

Same subject, same screen. The arm never reaches blinded roles.

Criteria

What to compare across modules

ModuleWhat to checkCapture
eCOA / ePRODevice model, licence handling, remindersBYOD in the browser; licence tracking; reminder ladder with quiet hours
eConsentIdentity, signatures, witness and representativeEmail OTP, investigator countersignature, witness and LAR signatures
Randomisation and supplyStratification, blinding, kit accountabilityBlock randomisation with stratification, kit dispensing under e-signature
EDCForms, edit checks, queries, SDVLocked approved forms, auto-queries, SDV per field
IntegrationOne audit trail or severalAll modules in one study and one audit trail
Cost and set-upPer-module fees and build timeFree sandbox; pay when you go live

In Capture

Consent, randomise, collect: one workflow

A participant signs eConsent, is screened with sequential numbering, randomised with stratification at enrolment, and receives their first questionnaire on their phone, all in the same study. Kits are dispensed under electronic signature, and every step is in one audit trail.

  • eConsent with verified signatures.
  • Stratified randomisation and kit dispensing.
  • ePRO on participants' phones.
Clinical trial randomization software
Randomize subject 01-007
Site 01: 3 randomization slots remaining17 / 20

Study status Live

Site activated Yes

Randomization list 42 allocations left

Has the subject signed the current informed consent?

YesNo
Next numberR-0013

Walk a test participant through the whole flow

Consent, randomise and complete a questionnaire in the free sandbox.

Compare options free

Fit

When a specialist vendor still makes sense

Very large global programmes with complex supply chains across many depots, many licensed instruments in dozens of languages, and a preference for fully managed services often choose specialist vendors for each module. That is a legitimate choice with its own trade-offs in cost and integration.

For most small and mid-sized studies, a single platform that the study team can build and amend is faster and simpler. Test both approaches against your protocol, and compare total cost including integration and reconciliation, not just licence fees. See best eConsent software and best ePRO software.

Evaluating a shortlist

Evaluation checklist

End-to-end demo

Consent, screening, randomisation and first questionnaire.

Blinding check

What a blinded user sees, including exports.

Kit accountability

Dispensing, returns and reports.

Audit trail

One trail or several to review.

Amendment test

How long a form change takes.

Total cost

Modules, integrations and per-site fees.

FAQ

Questions teams ask before they switch

Something not covered here? Ask us directly.

Can participants use their own phones?

Yes. Questionnaires open in the phone browser from a secure link.

Is there one audit trail?

Yes. EDC, ePRO, eConsent and randomisation share one study and one audit trail.

Who is this Signant Health alternatives page for?

Sponsors, CROs and academic teams comparing patient technology options, including teams using or evaluating Signant Health, who want to see a self-serve, unified option alongside it.

Does this page compare features line by line?

No. Vendors change their offerings, so we describe what to evaluate and where Capture fits. Confirm current capabilities and terms directly with Signant Health.

Can I test Capture before deciding?

Yes. The free sandbox has every feature with sample data, no credit card and no time limit.

Does Capture include randomisation and kit management?

Yes. Block randomisation with stratification, blinded and unblinded roles, and kit dispensing under electronic signature are in the same study as EDC.

Is eConsent included?

Yes, with email OTP verification, investigator countersignature, and witness and representative signatures.

Four modules, one study

Consent, randomise and collect in the free sandbox.

Compare options free