Vendor comparison · EDCUpdated September 29, 2026

Looking at TrialMaster alternatives? Start with how you want to build

Established EDC systems do the core job. The differences are in how studies get built and amended, what else is in the same system, and what it costs at your study size. Here is what to compare and where Capture fits.

  • AI-drafted forms from your protocol
  • EDC, ePRO and eConsent together
  • Free sandbox

Free sandbox · No credit card · 21 CFR Part 11 aligned

Build this form with AI

Question form

CRF or ePRO

Lab table

Analytes, units, ranges

Vital signs form: BP, pulse, temperature, respiratory rate, weight
Upload CSV, XLSX, PDF or DOCX
14 questionsReview before applying
  • 1. Systolic blood pressure

    Required · Number · mmHg · 0 dp

    Number
  • 2. Diastolic blood pressure

    Required · Number · mmHg · 0 dp

    Number
  • 3. Pulse rate

    Required · Number · beats/min

    Number
  • 4. Body temperature

    Required · Number · °C · 1 dp

    Number
  • 5. Position during measurement

    Required · Sitting, Supine, Standing

    Single choice
  • + 9 more questions
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The short version

  • TrialMaster is an established EDC system, originally from OmniComm Systems and now part of Anju Software.
  • Teams compare EDC alternatives when they want faster builds, self-serve amendments, ePRO and eConsent in the same system, or pricing that fits smaller studies.
  • Compare build ownership, edit checks and queries, integrated modules, exports, compliance controls and total cost.
  • Capture drafts visits and forms from your protocol with AI, and puts EDC, ePRO, eConsent and randomisation in one study with one audit trail.
  • Rebuild one of your real forms in each shortlisted system before choosing.

Why teams compare

Build and amendment speed

Most EDC systems can capture a visit, check a value and raise a query. What varies is how quickly a study gets from protocol to live, and how painful amendments are. In vendor-built models, every form change goes through a specification and change-control cycle. In self-serve models, your team makes the change, tests it and approves it, with the audit trail recording what changed.

Capture's AI Study Generator reads the protocol and drafts the visit schedule and forms for review, and the AI form builder drafts questions or lab tables from a description or an uploaded file. Nothing is saved without human review. See the CRF builder.

Configuration reuse

Organisations running several similar studies can export a study configuration and import it into a new study, copying forms and the visit schedule as a starting point.

app.capture.study · New study
Capture AI Study Generator: describe the study or upload a protocol to generate it

Criteria

What to compare between EDC systems

CriterionWhy it mattersCapture
Build ownershipSpeed and cost of builds and amendmentsYour team builds; AI drafts from the protocol
Edit checksClean data at entryRange and custom-value rules with auto-queries
Integrated modulesReconciliation and vendor countEDC, ePRO, eConsent and randomisation in one study
Compliance controlsPart 11 and GCP expectationsField-level audit trail, re-authenticated e-signatures, role-based access
ExportsAnalysis and submissionsCSV and Excel with a data dictionary, raw and decoded
CostFit for your study sizeFree sandbox; pay when you go live; no per-site fee

Data quality

Edit checks and a real audit trail from day one

Set range and custom-value edit checks yourself. When a site enters a value that breaks a rule, an auto-query is raised straight away. Approved forms are locked for live use, and every change is recorded field by field with who, when and why.

  • Auto-queries with configurable priority.
  • Locked approved forms.
  • Field-level audit trail.
Edit checks software
Vital signs · Systolic blood pressure

Edit checks / auto-queries

2
Auto-query

Type

Range High

Operator

Greater than

Value

180

Priority: High

Auto-query

Type

Range Low

Operator

Less than

Value

80

Priority: Normal

Query raised automatically

Value 192 violates limit (180). Please verify.

Bring a protocol and see it built

Upload it to the free sandbox and compare the draft with your current system.

Compare options free

Switching

Moving to a new EDC

Switch between studies where you can. Export form specifications or annotated CRFs from the current system and use them to draft the new build, then validate the new study with your usual testing. Historical data stays in its original export and is merged at analysis if needed.

If a mid-study switch cannot be avoided, plan a cut-over date, freeze data in the old system, and document the mapping between the two. See how to switch EDC vendors mid-study and the EDC vendor comparison guide.

Evaluating a shortlist

EDC evaluation checklist

Rebuild a real form

Time it in each system.

Make an amendment

Who does it and how long it takes.

Break an edit check

See the query workflow.

Review the audit trail

Readable, complete, exportable.

Export the data

Data dictionary and formats.

Get a full price

Build, licence, per-site and support.

FAQ

Questions teams ask before they switch

Something not covered here? Ask us directly.

Who is this TrialMaster alternatives page for?

Sponsors, CROs and academic teams comparing EDC options, including teams using or evaluating TrialMaster, who want to see a self-serve, unified option alongside it.

Does this page compare features line by line?

No. Vendors change their offerings, so we describe what to evaluate and where Capture fits. Confirm current capabilities and terms directly with TrialMaster.

Can I test Capture before deciding?

Yes. The free sandbox has every feature with sample data, no credit card and no time limit.

Can Capture draft forms from my existing CRFs?

Yes. The AI form builder drafts questions from an uploaded file or description, and the AI Study Generator drafts visits and forms from a protocol, all for your review.

Is Capture 21 CFR Part 11-aligned?

Capture provides a field-level audit trail, re-authenticated electronic signatures and role-based access control. Part 11 compliance also depends on how the sponsor validates and uses the system.

Compare Capture against your shortlist

Free sandbox with every feature. No sales call.

Compare options free