Capture vs TrialMaster: an established EDC or a modern self-serve build
TrialMaster has served sponsors and CROs for many years. Capture offers a different build model: AI drafting from the protocol, your team in control, and EDC, ePRO, eConsent and randomization in one study.
- Free sandbox, no sales call
- EDC, ePRO, eConsent, randomization
- Part 11-aligned controls
Free sandbox · No credit card · 21 CFR Part 11 aligned
Tests
5
Hands-on
4
To confirm
1
- Rebuild one of your real formsSame test, both systems
- Break an edit check and follow the querySame test, both systems
- Complete a questionnaire on a phoneSame test, both systems
- Sign a test eConsentSame test, both systems
- Compare total cost for your studyAsk both vendors
Capture vs TrialMaster: the short version
- TrialMaster is an EDC originally from OmniComm Systems and now part of Anju Software.
- Established EDC systems do the core job; differences show up in build model, integrated modules and cost.
- Capture's AI drafts the study from the protocol, and your team refines and approves it.
- Capture includes ePRO, eConsent and randomization in the same study and audit trail.
- Rebuild one real form in each system to compare effort.
0
sales calls needed to start building
1
audit trail across EDC, ePRO, eConsent and randomization
Free
sandbox with every feature, no time limit
EU + US
hosting in Frankfurt or N. Virginia
The comparison
When a mature EDC meets a new build model
Teams using long-established EDC systems often have deep experience and working processes. The reason to look elsewhere is rarely that the old system cannot capture data. It is usually the effort of each build, the number of systems around the EDC for patient data and randomization, or the commercial model for smaller studies.
Capture changes the build model: upload the protocol, review the draft, refine it and approve it. Participant questionnaires, consent and randomization are configured in the same study, so fewer systems need to be reconciled. See EDC implementation timeline.
What to compare
What to test when comparing Capture and TrialMaster
| Criterion | Why it matters | Capture |
|---|---|---|
| Study build | Time from protocol to testable study | AI drafts visits and forms from the protocol; your team reviews and approves |
| Modules in one study | Reconciliation and vendor count | EDC, ePRO, eConsent, randomization and kits with one audit trail |
| Data cleaning | Clean data at entry | Range and custom-value edit checks raise auto-queries; one query list |
| Exports | Analysis and future moves | CSV and Excel with a data dictionary, raw and decoded |
| Compliance controls | Part 11 and GCP expectations | Field-level audit trail, re-authenticated e-signatures, role-based access |
| Commercial model | Fit for your study size | Free sandbox; no setup fee; pay only when you go live |
This table shows Capture's answers only. Ask TrialMaster for theirs, and confirm current capabilities and terms directly with them.
Self-serve build
Your team builds and amends, with AI doing the drafting
The AI form builder drafts questions or lab tables from a description or an uploaded file, and the AI Study Generator drafts the schedule from your protocol. Nothing is saved without human review. Forms move from draft to approved and are locked for live use, so amendments are deliberate and recorded.
- Ten question types plus repeating table sections.
- Calculated fields such as BMI, BSA, eGFR and QTc.
- Configuration export and import between studies.
Question form
CRF or ePRO
Lab table
Analytes, units, ranges
- Number
1. Systolic blood pressure
Required · Number · mmHg · 0 dp
- Number
2. Diastolic blood pressure
Required · Number · mmHg · 0 dp
- Number
3. Pulse rate
Required · Number · beats/min
- Number
4. Body temperature
Required · Number · °C · 1 dp
- Single choice
5. Position during measurement
Required · Sitting, Supine, Standing
- + 9 more questions
One platform
EDC, ePRO, eConsent and randomization in one study
Sites enter data on locked, approved forms with edit checks that raise queries at entry. Participants complete questionnaires on their own phones and sign eConsent with verified signatures. Randomization and kit management run in the same study, and everything shares one field-level audit trail.
- One participant record across every module.
- No integrations to build or reconcile.
- Phase 1 through Phase 3.
Build the same form in Capture
Free sandbox with every feature. No credit card.
Fit
When TrialMaster fits, and when Capture does
TrialMaster is often a good fit for teams with a large base of existing TrialMaster studies, trained builders and validated processes they want to keep.
Capture fits teams that want faster builds with AI drafting, fewer systems around the EDC, and a free sandbox to test before any commitment.
Compliance controls
The controls inspectors look for, built in
Every change is written to an append-only, hash-chained audit trail with user, time, old and new value and reason. Electronic signatures require password re-authentication and carry a meaning statement. Roles separate sites, and identifying data is segregated from study data at the database layer.
- Field-level audit trail, never hard deleted.
- Re-authenticated e-signatures.
- Role-based access with site separation.
Weight changed 68.0 to 68.5 kg
Site coordinator · Reason: Transcription error
Query Q-0014 answered on Weight
Site coordinator · Reason: Source checked
Vital signs form locked
Data manager · Reason: Visit cleaned
Switching
Moving from TrialMaster to Capture
Move at study boundaries. Export annotated CRFs or specifications and upload them for AI drafting in Capture, then validate the new build with your usual testing.
Historical data stays in its original export and is combined at analysis if needed. See how to switch EDC vendors mid-study for when a mid-study move makes sense.
Evaluation
How to compare EDC vendors side by side
Same form in both systems
Build one real form with edit checks.
Site workflow
Enter data, raise and answer a query.
Participant workflow
Consent and a questionnaire on a phone.
Monitoring
Set SDV and review what a monitor sees.
Exports
Data dictionary, codes and labels.
Total cost
Setup, per-site and per-participant fees.
All comparisons
Compare Capture with other platforms
Every comparison uses the same approach: what to test, where each option fits, and Capture's own answers. See all of them on the comparisons hub at /compare.
Is Capture a TrialMaster alternative?
Yes, for teams that want AI-assisted self-serve builds and EDC, ePRO, eConsent and randomization in one study.
Can we reuse our existing CRFs?
Upload annotated CRFs or specifications, and the AI drafts the forms for your review.
Is validation documentation available?
Documentation to support sponsor validation and UAT is available on Enterprise plans.
Can I test Capture before deciding against TrialMaster?
Yes. The free sandbox includes every feature with sample data, no credit card and no time limit. You pay only when you go live.
How did you build this comparison?
From public positioning and the criteria teams tell us matter. We state only Capture's own capabilities as fact; confirm TrialMaster's current offering with them.
Keep exploring
Related pages
TrialMaster alternatives
A broader alternatives guide.
EDC implementation timeline
Where time goes.
Capture vs Castor
EDC, eCOA and eConsent from the Netherlands.
Capture vs Viedoc
EDC with patient modules, from Sweden.
Capture vs Medrio
EDC and eCOA for early-phase and mid-sized studies.
Capture vs OpenClinica
Cloud EDC with an open-source heritage.
Compare Capture against your shortlist
Free sandbox with every feature. No sales call.