Medidata Rave is built for large, global programmes and the organisations around them. Capture is built for teams that want to build their own study, start this month and run EDC, ePRO, eConsent and randomization in one place, from Phase 1 through Phase 3.
Free sandbox · No credit card · 21 CFR Part 11 aligned
Tests
5
Hands-on
4
To confirm
1
Capture vs Medidata Rave: the short version
0
sales calls needed to start building
1
audit trail across EDC, ePRO, eConsent and randomization
Free
sandbox with every feature, no time limit
EU + US
hosting in Frankfurt or N. Virginia
The comparison
Medidata Rave is designed for scale: large multinational programmes, complex designs, many sites and a sponsor organisation with data managers, programmers and validated processes around it. Many CROs build Rave studies for sponsors, and experienced Rave builders are easy to find. For that kind of programme, the ecosystem is a real strength.
The trade-off for smaller teams is the route to a live study: vendor or CRO builds, specification documents, change control and contracts sized for enterprise use. When the study is a 60-participant Phase 2 or an academic trial, that route can take longer than the team can afford. Capture was built for the other path: your team builds directly, tests in a sandbox and goes live when ready.
Study size is not a reason on its own to stay enterprise. Capture supports Phase 1 through Phase 3, with SDV set per field, freeze and lock, a site risk monitor and blinded roles. See EDC for Phase 3 clinical trials.
What to compare
| Criterion | Why it matters | Capture |
|---|---|---|
| Time to first build | Weeks saved before the first participant | AI drafts visits and forms from the protocol; build in the free sandbox |
| Who builds and amends | Speed and cost of changes | Your team, in a visual builder; approved forms locked, changes recorded |
| Modules included | Reconciliation and vendor count | EDC, ePRO, eConsent, randomization and kits in one study |
| Compliance controls | Part 11 and GCP expectations | Field-level audit trail, re-authenticated e-signatures, role-based access |
| Hosting | Data residency questions | EU (Frankfurt) or US (N. Virginia), chosen at setup |
| Commercial model | Fit for your study size | Free sandbox; no setup fee; pay only when you go live |
This table shows Capture's answers only. Ask Medidata Rave for theirs, and confirm current capabilities and terms directly with them.
Speed to start
Upload the protocol and the AI Study Generator drafts the visits, windows and forms for your team to review. Refine them in the visual builder, test with sample data in the free sandbox, and export a blank eCRF PDF for ethics submission. You pay only when you go live with real participants.

One platform
Sites enter data on locked, approved forms with edit checks that raise queries at entry. Participants complete questionnaires on their own phones and sign eConsent with verified signatures. Randomization and kit management run in the same study, and everything shares one field-level audit trail.

Upload a protocol to the free sandbox and compare the draft.
Fit
Rave is often the natural choice for large sponsors already standardised on Medidata, for programmes that rely on Medidata-specific integrations or established data standards workflows, and when a CRO partner will build and run the study in Rave.
Capture fits biotechs, academic groups and CROs that want to own the build, run EDC, ePRO, eConsent and randomization together, and start without an enterprise procurement cycle, from Phase 1 through Phase 3.
Compliance controls
Every change is written to an append-only, hash-chained audit trail with user, time, old and new value and reason. Electronic signatures require password re-authentication and carry a meaning statement. Roles separate sites, and identifying data is segregated from study data at the database layer.
Weight changed 68.0 to 68.5 kg
Site coordinator · Reason: Transcription error
Query Q-0014 answered on Weight
Site coordinator · Reason: Source checked
Vital signs form locked
Data manager · Reason: Visit cleaned
Switching
Switch at a natural break: a new study, not the middle of one. Export form specifications or annotated CRFs and upload them; Capture's AI form builder drafts the forms for review, and the template library covers standard forms such as demographics, vital signs, adverse events and concomitant medications.
Historical data stays in its original export and is combined at analysis if needed. If a mid-study move is unavoidable, plan a cut-over date and document the mapping. See how to switch EDC vendors mid-study.
Evaluation
Ask each vendor to build one real visit, not a demo study.
Contract, build, testing and training, in weeks.
EDC, ePRO, eConsent and randomization: one or several?
Who changes a form, and how long it takes.
Change a value and read the record.
Setup, licences, per-site fees and change orders.
All comparisons
Every comparison uses the same approach: what to test, where each option fits, and Capture's own answers. See all of them on the comparisons hub at /compare.
Yes, for teams that want a self-serve platform with EDC, ePRO, eConsent and randomization in one study, from Phase 1 through Phase 3.
Yes. Capture supports Phase 1 through Phase 3, with SDV per field, freeze and lock, site risk monitoring and blinded roles.
No. Your team builds with AI drafting from the protocol. CROs can also build and run studies in Capture.
Yes. The free sandbox includes every feature with sample data, no credit card and no time limit. You pay only when you go live.
From public positioning and the criteria teams tell us matter. We state only Capture's own capabilities as fact; confirm Medidata Rave's current offering with them.
Keep exploring
Medidata alternatives
A broader alternatives guide.
Medidata Rave vs Veeva Vault EDC
The enterprise head-to-head.
Capture vs Veeva Vault CDMS
Vault EDC and CDMS within Veeva's clinical platform.
Capture vs Oracle Clinical One
Oracle's unified clinical platform and InForm heritage.
Capture vs IQVIA EDC
EDC from IQVIA's technology portfolio.
Capture vs Merative Zelta
Formerly IBM Clinical Development.
Free sandbox with every feature. No credit card, no sales call.