Capture vs Medrio: speed for early-phase studies
Medrio and Capture both focus on getting studies live quickly. Capture adds AI drafting from the protocol, calculated safety fields at entry and randomization with kits, all in one self-serve study.
- Free sandbox, no sales call
- EDC, ePRO, eConsent, randomization
- Part 11-aligned controls
Free sandbox · No credit card · 21 CFR Part 11 aligned
Tests
5
Hands-on
4
To confirm
1
- Rebuild one of your real formsSame test, both systems
- Break an edit check and follow the querySame test, both systems
- Complete a questionnaire on a phoneSame test, both systems
- Sign a test eConsentSame test, both systems
- Compare total cost for your studyAsk both vendors
Capture vs Medrio: the short version
- Medrio offers EDC, eCOA, eConsent and related tools, with a focus on early-phase and mid-sized studies.
- Early-phase teams value speed: dense schedules, frequent safety data and quick amendments between cohorts.
- Capture's AI Study Generator drafts the schedule and forms from the protocol, and calculated fields such as QTcF, BMI and eGFR are shown during entry.
- Randomization, blinded roles and kit dispensing are part of the same study.
- Compare the build and amendment effort on a real early-phase protocol.
0
sales calls needed to start building
1
audit trail across EDC, ePRO, eConsent and randomization
Free
sandbox with every feature, no time limit
EU + US
hosting in Frankfurt or N. Virginia
The comparison
What early-phase studies need from a platform
Phase 1 and early Phase 2 studies have dense schedules, many timed assessments and safety data that drives cohort decisions. Protocols change between cohorts, so the platform has to make amendments quick and traceable. Both Medrio and Capture aim at this kind of study, which is why they are often compared.
Capture handles timed assessments as repeating rows with their own audit trail, calculates common safety values during entry, and keeps forms locked once approved so each amendment is deliberate and recorded. See EDC for Phase 1 clinical trials.
What to compare
What to test when comparing Capture and Medrio
| Criterion | Why it matters | Capture |
|---|---|---|
| Study build | Time from protocol to testable study | AI drafts visits and forms from the protocol; your team reviews and approves |
| Safety calculations | Fewer manual errors | QTcF, QTc Bazett and Fridericia, BMI, BSA, eGFR and more, calculated at entry |
| Amendments | Cohort-to-cohort changes | Draft and approved form states; approved forms locked; changes in the audit trail |
| Modules in one study | Reconciliation and vendor count | EDC, ePRO, eConsent, randomization and kits with one audit trail |
| Data cleaning | Clean data at entry | Range and custom-value edit checks raise auto-queries; one query list |
| Commercial model | Fit for your study size | Free sandbox; no setup fee; pay only when you go live |
This table shows Capture's answers only. Ask Medrio for theirs, and confirm current capabilities and terms directly with them.
Self-serve build
Your team builds and amends, with AI doing the drafting
The AI form builder drafts questions or lab tables from a description or an uploaded file, and the AI Study Generator drafts the schedule from your protocol. Nothing is saved without human review. Forms move from draft to approved and are locked for live use, so amendments are deliberate and recorded.
- Ten question types plus repeating table sections.
- Calculated fields such as BMI, BSA, eGFR and QTc.
- Configuration export and import between studies.
Question form
CRF or ePRO
Lab table
Analytes, units, ranges
- Number
1. Systolic blood pressure
Required · Number · mmHg · 0 dp
- Number
2. Diastolic blood pressure
Required · Number · mmHg · 0 dp
- Number
3. Pulse rate
Required · Number · beats/min
- Number
4. Body temperature
Required · Number · °C · 1 dp
- Single choice
5. Position during measurement
Required · Sitting, Supine, Standing
- + 9 more questions
One platform
EDC, ePRO, eConsent and randomization in one study
Sites enter data on locked, approved forms with edit checks that raise queries at entry. Participants complete questionnaires on their own phones and sign eConsent with verified signatures. Randomization and kit management run in the same study, and everything shares one field-level audit trail.
- One participant record across every module.
- No integrations to build or reconcile.
- Phase 1 through Phase 3.
Build the same form in Capture
Free sandbox with every feature. No credit card.
Fit
When Medrio fits, and when Capture does
Medrio is often a good fit for teams and CROs with existing Medrio templates and processes, particularly those running many similar early-phase studies on it.
Capture fits early-phase teams that want an AI-drafted build from the protocol, safety calculations at entry and randomization in the same study, with a free sandbox to test first.
Compliance controls
The controls inspectors look for, built in
Every change is written to an append-only, hash-chained audit trail with user, time, old and new value and reason. Electronic signatures require password re-authentication and carry a meaning statement. Roles separate sites, and identifying data is segregated from study data at the database layer.
- Field-level audit trail, never hard deleted.
- Re-authenticated e-signatures.
- Role-based access with site separation.
Weight changed 68.0 to 68.5 kg
Site coordinator · Reason: Transcription error
Query Q-0014 answered on Weight
Site coordinator · Reason: Source checked
Vital signs form locked
Data manager · Reason: Visit cleaned
Switching
Moving from Medrio to Capture
Start a new study in Capture. Upload the protocol for a draft schedule, and upload existing form specifications for the AI to draft the forms. Use the configuration export to reuse your build for the next study.
Historical data stays in its original export and is combined at analysis if needed. See how to switch EDC vendors mid-study for when a mid-study move makes sense.
Evaluation
How to compare EDC vendors side by side
Same form in both systems
Build one real form with edit checks.
Site workflow
Enter data, raise and answer a query.
Participant workflow
Consent and a questionnaire on a phone.
Monitoring
Set SDV and review what a monitor sees.
Exports
Data dictionary, codes and labels.
Total cost
Setup, per-site and per-participant fees.
All comparisons
Compare Capture with other platforms
Every comparison uses the same approach: what to test, where each option fits, and Capture's own answers. See all of them on the comparisons hub at /compare.
Is Capture a Medrio alternative?
Yes, particularly for early-phase and mid-sized studies that want a self-serve build with AI drafting.
Does Capture calculate QTc?
Yes. QTc Bazett and Fridericia and QTcF from heart rate are calculated fields shown during entry.
Can we reuse a study build?
Yes. Export a study configuration and import it into a new study as a starting point.
Can I test Capture before deciding against Medrio?
Yes. The free sandbox includes every feature with sample data, no credit card and no time limit. You pay only when you go live.
How did you build this comparison?
From public positioning and the criteria teams tell us matter. We state only Capture's own capabilities as fact; confirm Medrio's current offering with them.
Keep exploring
Related pages
EDC for Phase 1 trials
Early-phase data.
EDC for first-in-human studies
FIH schedules.
Capture vs Castor
EDC, eCOA and eConsent from the Netherlands.
Capture vs Viedoc
EDC with patient modules, from Sweden.
Capture vs OpenClinica
Cloud EDC with an open-source heritage.
Capture vs Clinion
eClinical platform including EDC.
Compare Capture against your shortlist
Free sandbox with every feature. No sales call.