Capture vs 4G Clinical: specialist RTSM or built into the EDC
4G Clinical focuses on RTSM for randomization and trial supply. Capture builds randomization, blinding and kits into the EDC, configured once at setup by your team.
- Free sandbox, no sales call
- EDC, ePRO, eConsent, randomization
- Part 11-aligned controls
Free sandbox · No credit card · 21 CFR Part 11 aligned
Tests
5
Hands-on
4
To confirm
1
- Randomize a test participant with strataSame test, both systems
- Check what a blinded user seesSame test, both systems
- Test emergency unblindingSame test, both systems
- Dispense and return a kitSame test, both systems
- Map your supply chain needsAsk both vendors
Capture vs 4G Clinical: the short version
- 4G Clinical is an RTSM provider focused on randomization and trial supply management.
- Specialist RTSM providers compete on configuration speed and supply sophistication.
- Capture configures arms, blocks, strata and caps once at setup, with no separate system to integrate.
- Blinded roles, emergency unblinding and kit accountability are built in.
- Compare configuration effort and total cost including the EDC integration.
0
sales calls needed to start building
1
audit trail across EDC, ePRO, eConsent and randomization
Free
sandbox with every feature, no time limit
EU + US
hosting in Frankfurt or N. Virginia
The comparison
Configuration effort, then integration effort
RTSM vendors have worked to shorten configuration time. The remaining effort in a two-system setup is the integration with the EDC: agreeing data flows, testing them, and reconciling allocation and dispensing records throughout the study.
Capture removes that step for studies whose supply needs fit inside the EDC. Randomization happens at enrolment, allocation is logged in the audit trail, and kit records sit with visit data. See block randomization software for design options.
What to compare
What to test when comparing Capture and 4G Clinical
| Criterion | Why it matters | Capture |
|---|---|---|
| Randomization design | Balance and allocation concealment | Block randomization with stratification and enrolment caps |
| Blinding | Protecting the trial | Blinded roles never receive the treatment arm, including in exports |
| Kit management | Dispensing and accountability | Kit dispensing under e-signature; accountability report and export |
| Configuration | Time to go live | Set once at setup by your team; test in the sandbox |
| Complex supply | Depots and forecasting | Map requirements; complex supply may need a specialist RTSM |
| Commercial model | Fit for your study size | Free sandbox; no setup fee; pay only when you go live |
This table shows Capture's answers only. Ask 4G Clinical for theirs, and confirm current capabilities and terms directly with them.
Randomization
Randomization and kits inside the EDC
Set arms, block size, stratification factors and enrolment caps once at setup. Allocation happens at enrolment, the same way at every site, and is logged in the audit trail. An unblinded administrator owns the randomization and medication lists, and kits are dispensed under electronic signature.
- Stratified block randomization with caps.
- Kit dispensing and accountability.
- Allocation logged in the audit trail.
1 of 2 kits confirmed
Blinding
Blinding enforced on the server
Blinded roles never receive the treatment arm, not even in the data behind the screen or in exports. Investigators keep emergency unblinding, and the study owner can approve an unblinding request without seeing the answer. Every allocation and unblinding is logged.
- Treatment arm never sent to blinded users.
- Emergency unblinding, logged.
- Approvals without revealing the arm.
Study coordinator
Subject 01-004
Randomized · R-0012
KitK-10418
Arm columnNot sent
Unblinded administrator
Subject 01-004
Randomized · R-0012
KitK-10418
Arm columnA
Same subject, same screen. The arm never reaches blinded roles.
Randomize and dispense in the sandbox
Try it as a blinded and an unblinded user.
Fit
When 4G Clinical fits, and when Capture does
4G Clinical is often a good fit for trials with complex supply chains that need a specialist RTSM with advanced supply configuration.
Capture fits studies that want randomization, blinding and kits in the EDC, configured by the study team without an integration.
One platform
EDC, ePRO, eConsent and randomization in one study
Sites enter data on locked, approved forms with edit checks that raise queries at entry. Participants complete questionnaires on their own phones and sign eConsent with verified signatures. Randomization and kit management run in the same study, and everything shares one field-level audit trail.
- One participant record across every module.
- No integrations to build or reconcile.
- Phase 1 through Phase 3.
Switching
Moving from 4G Clinical to Capture
Configure randomization in a Capture sandbox study and test it as blinded and unblinded users before going live.
Keep completed studies' allocation records with their original exports, and recreate designs for new studies.
Evaluation
How to evaluate randomization and supply options
Randomization design
Blocks, strata and enrolment caps.
Blinded view
Screens and exports for blinded users.
Emergency unblinding
Who can, and what is logged.
Kit accountability
Dispensing, returns and reports.
Supply complexity
Depots, temperature control and resupply rules.
EDC link
Integration or the same system.
All comparisons
Compare Capture with other platforms
Every comparison uses the same approach: what to test, where each option fits, and Capture's own answers. See all of them on the comparisons hub at /compare.
Is Capture an RTSM?
Capture includes randomization, blinding and kit management inside the EDC. Very complex supply chains may still need a specialist RTSM.
Is Capture a 4G Clinical alternative?
For studies with straightforward supply, yes.
Can I test randomization before going live?
Yes, in the free sandbox as blinded and unblinded users.
Can I test Capture before deciding against 4G Clinical?
Yes. The free sandbox includes every feature with sample data, no credit card and no time limit. You pay only when you go live.
How did you build this comparison?
From public positioning and the criteria teams tell us matter. We state only Capture's own capabilities as fact; confirm 4G Clinical's current offering with them.
Randomization without another system
Blinding and kits in the EDC. Free sandbox.