Comparison · ClarioUpdated September 29, 2026

Capture vs Clario: services, software, or both

Clario combines endpoint technology with specialist services such as cardiac safety and imaging. If what you need is ePRO software your team can run, in the same study as your EDC, Capture is built for that.

  • Free sandbox, no sales call
  • EDC, ePRO, eConsent, randomization
  • Part 11-aligned controls

Free sandbox · No credit card · 21 CFR Part 11 aligned

Evaluation · Clario vs Capture

Tests

5

Hands-on

4

To confirm

1

  • Consent a test participant remotelySame test, both systems
  • Complete a diary on your own phoneSame test, both systems
  • Miss an entry and watch the remindersSame test, both systems
  • See participant data next to site dataSame test, both systems
  • Compare total cost for your studyAsk both vendors
Test both on your own protocol

Capture vs Clario: the short version

  • Clario, formed from the combination of ERT and Bioclinica, is a large endpoint technology provider known for eCOA, cardiac safety and medical imaging.
  • Clario's strength is breadth: endpoint technology plus specialist services for large trials.
  • Many studies need only part of that: participant questionnaires and diaries that feed the EDC.
  • Capture is software, not a core lab. It holds results from specialist services, but does not replace ECG or imaging reading.
  • For ePRO, Capture offers BYOD questionnaires, licence tracking and compliance tools in the same study as EDC.

0

sales calls needed to start building

1

audit trail across EDC, ePRO, eConsent and randomization

Free

sandbox with every feature, no time limit

EU + US

hosting in Frankfurt or N. Virginia

The comparison

Separate the service question from the software question

Some trials need centralised ECG reading, imaging core labs and fully managed eCOA from one provider. Others need a good ePRO tool the study team can run, next to their EDC. Treating these as one decision can lead to buying more than the study needs, or to a separate eCOA system that must be integrated with the EDC.

Split the question: which specialist services does the protocol require, and which software will the team run? Capture answers the software side: EDC, ePRO, eConsent and randomization in one study, with results from specialist services recorded alongside. See best ePRO software.

What to compare

What to test when comparing Capture and Clario

CriterionWhy it mattersCapture
Device modelCost and participant frictionBYOD in the browser with no app; clinic devices supported
Licensed instrumentsLicence tracking and faithful migrationLicence number, holder and expiry per form; collection blocked if lapsed
Compliance toolsMissing diary days are missing dataWindows, three-step reminder ladder, quiet hours, at-risk participants flagged
Link to site dataReconciliation effortePRO, eConsent and EDC in one study and one audit trail
Specialist servicesECG and imaging readingNot provided; results from reading services can be recorded in the study
Commercial modelFit for your study sizeFree sandbox; no setup fee; pay only when you go live

This table shows Capture's answers only. Ask Clario for theirs, and confirm current capabilities and terms directly with them.

Participant data

ePRO on participants' own phones, in the same audit trail

Participants open a secure link with no app to install. Diaries and questionnaires follow the schedule with completion windows, and reminders go out when a task is due, the next day and before the window closes, respecting quiet hours in each participant's time zone. Compliance is visible by study, country and site.

  • BYOD in the browser, no app store.
  • Licence tracking for licensed instruments.
  • At-risk participants flagged.
ePRO software for clinical trials
ePRO compliance by site
Site 0194%
Site 0281%
Site 0358%

At-risk participants

03-0073 diary entries missedReminder delivered
03-011Week 4 questionnaire overdueEmail bounced

eConsent

Consent with evidence you can hand to an inspector

Participants sign on screen after confirming a one-time email code and acknowledging that the signature is legally binding. The investigator countersigns with password re-authentication. Witness and legally authorised representative signatures are supported, and each signature is linked to the exact document content.

  • Remote or in-clinic signing.
  • Signed PDF with audit trail.
  • Consent in the same study as the data.
eConsent software for clinical trials
Electronic signature

Meaning of signature

I have reviewed this adverse event and confirm the assessment of seriousness, severity and causality.

Signer

Dr. A. Ozola, PI

Password

••••••••••

Verified on the serverAutofill blockedSingle-use token
Sign

Walk through the participant journey

Consent and complete a diary on your own phone in the free sandbox.

Compare it free in the sandbox

Fit

When Clario fits, and when Capture does

Clario is often the natural choice for large trials that need centralised cardiac safety, imaging and fully managed eCOA from one provider.

Capture fits studies that need ePRO the team can build and run, in the same study as EDC, eConsent and randomization.

One platform

EDC, ePRO, eConsent and randomization in one study

Sites enter data on locked, approved forms with edit checks that raise queries at entry. Participants complete questionnaires on their own phones and sign eConsent with verified signatures. Randomization and kit management run in the same study, and everything shares one field-level audit trail.

  • One participant record across every module.
  • No integrations to build or reconcile.
  • Phase 1 through Phase 3.
EDC for Phase 3 clinical trials
app.capture.study · Dashboard
Capture study dashboard with enrolment, compliance, safety overview and site risk monitor

Switching

Moving from Clario to Capture

Keep specialist reading services where the protocol needs them, and move the questionnaire and data capture side to Capture for new studies.

Switch at study boundaries rather than mid-study, especially for licensed instruments, whose electronic versions usually need the licence holder's approval in each new system.

Evaluation

How to evaluate patient-facing technology

Participant journey

Consent, onboarding and first questionnaire on a phone.

Device model

BYOD, provisioned devices or both.

Compliance tools

Windows, reminders and at-risk alerts.

Licensed instruments

Who migrates them and how licences are tracked.

Link to EDC

One audit trail or an integration.

Total cost

Build, per-participant and device costs.

All comparisons

Compare Capture with other platforms

Every comparison uses the same approach: what to test, where each option fits, and Capture's own answers. See all of them on the comparisons hub at /compare.

FAQ

Questions teams ask before they switch

Something not covered here? Ask us directly.

Is Capture a Clario alternative?

For eCOA and ePRO software, yes. Capture does not provide cardiac safety or imaging reading services.

Can Capture store results from central readers?

Yes. Results from specialist services can be recorded as structured fields in the study.

Do participants need an app?

No. Questionnaires open in the phone browser from a secure link.

Can I test Capture before deciding against Clario?

Yes. The free sandbox includes every feature with sample data, no credit card and no time limit. You pay only when you go live.

How did you build this comparison?

From public positioning and the criteria teams tell us matter. We state only Capture's own capabilities as fact; confirm Clario's current offering with them.

Participant data in the same study as everything else

Free sandbox with every feature.

Compare it free in the sandbox